Dr Althea PDRN Reju Creams and 345 Explained

Dr Althea's PDRN creams should not be treated as one formula with three strengths. Current manufacturer descriptions differ: Reju 5000 is described as fermentation-derived vegan PDRN, whereas Reju 10000 is described as salmon-derived. The current global 345 Relief Cream ingredient list also includes Sodium DNA.2 3 4

The right starting point is the exact product and market version, not the highest number. This is a research-based comparison, not a hands-on test or a clinical ranking.

Reju 2000

The official Reju 2000 page describes a lightweight daily moisturiser and an ointment-to-gel texture.1 Its accessible main product text did not provide a clear 2,000 ppm disclosure during this review. We therefore do not convert the product name into a verified concentration.

If dose or source determines your choice, request confirmation for your exact tube. A search-page title and a retailer description can contain older or inconsistent wording; neither should outweigh a current, product-specific manufacturer response.

Reju 5000

The current official page explicitly describes 5,000 ppm probiotic-derived vegan PDRN from fermented ingredients. It also publishes an ingredient list including Sodium DNA.2

This differs from the assumption that every Reju cream uses salmon. It also shows why an ingredient name alone may not reveal sourcing. If strict vegan certification is important, verify the whole-product claim and market version, not just the ingredient's origin.

Reju 10000

The official product description states 10,000 ppm salmon-derived PDRN and an ointment-style gel texture.3 On the same concentration basis, that figure is 1%. It is a manufacturer disclosure, not an independently measured value for the tube you receive.

The larger number does not prove better clinical results, greater tolerability or better value. Comparing different sources and formulations requires more than arithmetic.

The current 345 Relief Cream

The global 345 page currently lists Sodium DNA alongside ingredients including niacinamide, panthenol and ceramide NP.4 That should not be used to claim that every older 345 product or every regional tube has the same formula.

Likewise, a story about a rice-and-centella PDRN version needs to match the actual pack being discussed. We do not infer a confirmed DNA source for all 345 creams solely from the shared product name.

The product is a moisturiser, not a substitute for medical acne treatment. Tea tree leaf water should also not be automatically treated as equivalent to concentrated tea tree essential oil when discussing formula risks.

What the comparison cannot establish

We have not verified a suitable head-to-head clinical study showing which of these creams works best. Manufacturer texture descriptions and individual concentration claims cannot supply that answer.

It is especially misleading to advise starting at 2000 and moving up to 10000 as though these were a prescribed titration schedule. Higher branding numbers do not create a medically necessary progression. You can choose a moisturiser by suitability without working through a range.

A practical buying check

• Match the full name and pack size with the description you are relying on.
• Check the ingredient panel on the actual product, especially if replacing an older tube.
• Obtain source confirmation for fish allergy or animal-free requirements.
• Compare delivered cost per unit and seller reliability.
• Treat claims of clinical equivalence, universal gentleness or dramatic repair cautiously unless the supporting study is available.

If a seller gives a conflicting source description, pause and ask rather than choosing whichever answer you prefer. This is particularly important for an allergy-related decision.

Using a cream in an ordinary routine

Follow the pack, introduce only one new product and use it as the moisturiser step. Toner and serum are optional. Keep daytime sunscreen separate and after skincare.

For damaged skin, persistent dermatitis or care after a procedure, use professional guidance specific to your situation. The Reju name is not permission to put a cosmetic on a wound.

See the site's Dr Althea 345 product page and PDRN vegan guide for related context.

Common questions

Is every Dr Althea PDRN cream salmon derived

No. The current Reju 5000 description specifies fermentation-derived vegan PDRN; Reju 10000 specifies salmon.2 3

Does 10000 mean the best results

No. It is a product concentration claim, not a validated outcome ranking.

Does every 345 cream contain PDRN

The current global ingredient list includes Sodium DNA. Check your own version rather than extending that to every historical or regional formula.

Should I move up through the Reju numbers

There is no evidence-based progression established here. Choose the product that suits your needs rather than treating the range like medicine strengths.

Related reading

• Choosing a PDRN Cream for Your Skin and Routine
• Dr Reju All PDRN Cream and Serum Review

Sources

• 1. Dr Althea official PDRN Reju 2000 Cream
• 2. Dr Althea official PDRN Reju 5000 Cream
• 3. Dr Althea official PDRN Reju 10000 Cream
• 4. Dr Althea official current 345 Relief Cream ingredient list

About this article

Korean PDRN research-based editorial. Sources checked on 16 October 2026. Manufacturer and retailer information can change; the pack supplied to you takes priority for ingredients and directions. This article does not report hands-on testing or an independent clinical trial. It provides general information, not personal medical advice.