Anua PDRN Range Review: Serum, Cream, Toner, and Glow Pads Formulations

Anua's PDRN range offers different ways to add skincare, not a requirement to use every product together. Choose a cream if you need a moisturiser, a serum if you want an optional layer, or a spray if you prefer that application format. Buying the entire range is not necessary to try PDRN.

This is a research-based range overview, not a hands-on wear test. Product descriptions and brand test claims are distinguished from independent evidence throughout.

Understand the product names

Searches for the Anua PDRN cream usually mean the PDRN Hyaluronic Acid 100 Moisturizing Cream, and the Anua PDRN serum is the PDRN Hyaluronic Acid Capsule 100 Serum.

The PDRN Hyaluronic Acid 100 Moisturizing Cream is a moisturiser. The PDRN Hyaluronic Acid Capsule 100 Serum is a separate product. Anua's US site currently calls its capsule mist the PDRN Collagen Glow Facial Serum Spray, while the page address retains the older hydrating-capsule-mist name.1 2 3

Those overlapping names can make shop comparisons confusing. Match the full name, size, ingredient panel and market version. A number in a product name should not be interpreted as a percentage without an explicit explanation from the brand.

Choose by the job your routine needs

Cream for the moisturiser step

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The cream is the relevant option if you need a daily moisturiser. Anua identifies salmon-derived PDRN in its description.1 Whether you like its texture is a personal question; we have not tested its claims about makeup compatibility on different skins.

If your current moisturiser already keeps skin comfortable, there is no clear reason to replace it just to include the same ingredient as your serum. Compare comfort, tolerance and ongoing cost first.

Serum for an optional layer

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The Capsule 100 Serum is listed as a separate serum product.3 It may fit a routine that already has a suitable cream. A serum is not automatically more concentrated or more effective than a moisturiser, however. Do not infer a PDRN dose from a hyaluronic-acid blend claim.

Spray for application preference

Anua's current serum spray page states 2,000 ppm PDRN.2 That is a manufacturer disclosure, not a reason to conclude that spraying beats a cream. The amount deposited depends on use, and the finished formulations differ.

A spray can be convenient, but it does not replace sun protection. Avoid treating it as a reason to rub or repeatedly disturb sunscreen during the day.

Toner for a watery first layer

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The PDRN 100 Hyaluronic Acid Booster Toner is a watery hydrating toner. Its published ingredient list combines salmon-derived sodium DNA with humectants, panthenol and hyaluronic-acid and collagen components, and it is intended to ease post-cleansing tightness before later layers. It suits a routine that lacks a hydrating first step; it does not need to be paired with the serum or cream. See the Anua PDRN Booster Toner product page.

Glow pads for convenience

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The PDRN 100 Hyaluronic Acid Glow Pads are dual-textured, essence-soaked toner pads. They are primarily a hydrating convenience format rather than an exfoliating treatment, so avoid scrubbing with them. If you already use a toner, the pads are an alternative format, not an extra step you need. See the Anua PDRN Glow Pads product page.

How to read Anua test claims

Anua publishes test-result summaries on its product pages, so it would be inaccurate to say the brand provides no testing information.1 2 Those summaries are not the same as an independently replicated trial proving PDRN's contribution to the whole formula.

Ask whether a reported result measures hydration, appearance, elasticity or something else. Was there a comparison product? How many participants were studied? Were they using this product alone? A percentage from one test cannot fairly rank two unrelated products tested in different ways.

Source and sensitive skin considerations

The salmon-derived description matters if you avoid animal ingredients. A cruelty-free claim concerns a different question from vegan status. If you have a fish allergy, do not rely on the phrase purified DNA as proof of safety; ask the manufacturer and a clinician about the exact product.

Sensitive skin also requires more than a reassuring range name. Fragrance status, other actives, previous reactions and current irritation matter. Try only one new product at a time; stop if it causes persistent stinging, redness or itching.

A simple starting point

Keep cleanser, an appropriate moisturiser and sun protection in place. Add a single Anua product only if it has a clear role. Take notes about comfort and tolerance rather than expecting a fixed week-by-week transformation. If a product adds expense or irritation without an identifiable benefit, you do not need to continue it.

Read the Anua cream product page or the Anua serum product page for product-specific information.

Common questions

Do I need the serum and cream together

No. Choose based on the missing step in your existing routine, not the assumption that matching products must be layered.

Is all Anua skincare vegan

Do not make a brand-wide assumption. The reviewed PDRN cream is described as salmon-derived; assess each product separately.

Is Anua PDRN an acne treatment

A moisturiser or serum is not a substitute for assessment and evidence-based treatment of persistent acne.

Can I use the Anua PDRN toner every day

Anua presents it as a daily toner after cleansing. Use it according to the pack directions and stop if it causes persistent stinging, redness or itching.

Are the Anua PDRN glow pads exfoliating

They are described as hydrating toner pads rather than an exfoliating treatment. Wipe gently; they are not a reason to rub irritated skin.

Related reading

• Best PDRN creams and toners compared
• Anua PDRN Hyaluronic Acid Cream Review
• Anua PDRN Spray and Hydrating Capsule Mist Review

Sources

• 1. Anua official PDRN cream product information
• 2. Anua official PDRN serum spray product information
• 3. Anua PDRN serum listing at Ulta

• Lampridou S et al. (2025) — The effectiveness of polynucleotides in aesthetic medicine: a systematic review: mainly injected polynucleotides; shows why clinic results do not transfer to leave-on products.

• Marques C et al. (2025) — From PDRNs to PNs: scientific definitions, molecular insights and clinical applications: definitions of PDRN and polynucleotides.

• Ye et al. (2026) — Topical medium-length PDRN in photodamaged skin: an early, small study of a topical PDRN formula — not of Anua's products.

About this article

Korean PDRN research-based editorial. Sources checked on 16 October 2026. Manufacturer and retailer information can change; the pack supplied to you takes priority for ingredients and directions. This article does not report hands-on testing or an independent clinical trial. It provides general information, not personal medical advice.